Quest Diagnostics | 9 GI targets

About Gastrointestinal Pathogen Panel, Real-Time PCR

Gastrointestinal Pathogen Panel, Real-Time PCR is a qualitative, culture-independent nucleic acid test for the simultaneous detection of 9 possible causes of infectious diarrhea.

Qualitative, culture-independent nucleic acid test
Detects 7 pathogens and 2 toxins—5 bacteria, 2 viruses, and 2 bacterial (Shiga) toxin-related genes—from a single test
Requires only a single sample, using the same transport tube used for stool culture
Turnaround time of 24-72 hours
Follows Infectious Disease Society of America (IDSA) testing guidelines^1,2

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Why test?

Infectious diarrhea is a growing problem that may require testing. In the US alone, it is responsible for 179 million outpatient visits, nearly 500,000 hospitalizations, and >5,000 deaths annually.¹

For some pathogens, an organism-specific diagnosis is required¹
Inflammatory diarrhea may be more severe and require more than simple hydration for the patient
Early diagnosis of an acute episode of diarrhea can lead to alleviation of symptoms and prevent secondary transmission

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Asking the right questions to identify risk

Culture versus CIDT

For infectious diarrhea, guidelines support the use of culture or culture-independent diagnostic tests (CIDTs) for the etiologic pathogens of highest prevalence in the United States.^1,2

There are important differences, however:

Traditional culture-based tests are manual, slow, therefore time consuming, and inconclusive in determining the cause(s) of infectious diarrhea.²
CIDTs such as polymerase chain reaction (PCR) may provide a more automated and quick alternative to culture-based methods.²
PCR testing appears to be rapid, sensitive, and specific in determining the cause(s) of infectious diarrhea.²

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Test Name	Test Code^a	CPT Code(s)^b
Gastrointestinal Pathogen Panel, Real-Time PCR (see above for more information) Includes Campylobacter Group, Salmonella Species, Shigella Species, Vibrio Group, Yersinia enterocolitica, Shiga toxin 1, Shiga toxin 2, Norovirus GI/GII, and Rotavirus A	38470	87506
Bacteria
Campylobacter, Culture	4475	87046
Campylobacter species Antigen, EIA	16302	87449
Clostridium difficile Toxin B, Qualitative, Real-Time PCR	16377	87493
Clostridium difficile Toxin/GDH with Reflex to PCR	91664	87449, 87324 and 87493, if performed
Escherichia coli O157, Culture	8631	87046
Lactoferrin, Qualitative, Stool	10156	83630
Helicobacter pylori, Antigen, EIA, Stool	34838	87338
Helicobacter pylori, Urea Breath Test	14839	83013
Helicobacter pylori, Urea Breath Test, Pediatric	92491	83013
Salmonella/Shigella/Campylobacter, Culture and Shiga Toxin with Reflex to E. coli O157, Culture	10108	87427, 87046 if performed
Salmonella and Shigella, Culture	10019	87045
Shiga Toxins, EIA with Reflex to E. coli O157, Culture	30264	87329, 87177, if performed and 87209, if performed
Vibrio, Culture	4489	87046
Yersinia, Culture	4487	87046
Viruses
Adenovirus, Qualitative, Real-Time PCR	16046	87798
Norovirus, EIA, Stool	15544	87449
Norovirus RNA, Qualitative Real-Time PCR	19098	87798
Rotavirus Antigen Detection	706	87425
Parasites
Cryptosporidium Antigen, EIA	90389	87328
Cryptosporidium Antigen, DFA	37213	87015, 87272
Cyclospora and Isospora Examination	10018	87015, 87207
Entamoeba histolytica Antigen, EIA	34964	87337
Giardia Antigen, EIA, Stool	8625	87329
Giardia Antigen with Reflex to Ova and Parasites	17297	87329, 87177, 87209
Giardia and Cryptosporidium Antigen Panel	39480	87015, 87272, 87329
Ova and Parasites, Concentrate and Permanent Smear	681	87177, 87209
Ova and Parasites, Concentrate and Permanent Smear, 2 Specimens	6653	87177 (x2), 87209 (x2)
Ova and Parasites, Concentrate and Permanent Smear, 3 Specimens	6652	87177 (x3), 87209 (x3)

^a Test codes may vary by location. Please contact your local laboratory or go to QuestDiagnostics.com/TestCenter for more information.

^b The CPT codes provided are based on American Medical Association guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed. Reflex tests will be performed at an additional charge. Panel components can be ordered separately.

Test for 7 pathogens and 2 toxins at once—so you can move to optimal treatment faster

Our GI pathogen panel tests for multiple causes of infectious diarrhea with the speed and accuracy of molecular testing to help you optimize treatment.

About Gastrointestinal Pathogen Panel, Real-Time PCR

Why test?

Culture versus CIDT

Save time with Quanum® Lab Services Manager

Determine a course of action with the help of our GI pathogen panel

Gastrointestinal Pathogen Panel, Real-Time PCR from Quest tests for 7 pathogens and 2 toxins as recommended by IDSA guidelines, so you can optimize treatment sooner.

Test Name

Test Codea

CPT Code(s)b

Gastrointestinal Pathogen Panel, Real-Time PCR (see above for more information)

Bacteria

Campylobacter, Culture

Campylobacter species Antigen, EIA

Clostridium difficile Toxin B, Qualitative, Real-Time PCR

Clostridium difficile Toxin/GDH with Reflex to PCR

Escherichia coli O157, Culture

Lactoferrin, Qualitative, Stool

Helicobacter pylori, Antigen, EIA, Stool

Helicobacter pylori, Urea Breath Test

Helicobacter pylori, Urea Breath Test, Pediatric

Salmonella/Shigella/Campylobacter, Culture and Shiga Toxin with Reflex to E. coli O157, Culture

Salmonella and Shigella, Culture

Shiga Toxins, EIA with Reflex to E. coli O157, Culture

Vibrio, Culture

Yersinia, Culture

Viruses

Adenovirus, Qualitative, Real-Time PCR

Norovirus, EIA, Stool

Norovirus RNA, Qualitative Real-Time PCR

Rotavirus Antigen Detection

Parasites

Cryptosporidium Antigen, EIA

Cryptosporidium Antigen, DFA

Cyclospora and Isospora Examination

Entamoeba histolytica Antigen, EIA

Giardia Antigen, EIA, Stool

Giardia Antigen with Reflex to Ova and Parasites

Giardia and Cryptosporidium Antigen Panel

Ova and Parasites, Concentrate and Permanent Smear

Ova and Parasites, Concentrate and Permanent Smear, 2 Specimens

Ova and Parasites, Concentrate and Permanent Smear, 3 Specimens

Learn more about our comprehensive testing for GI distress

Save time with Quanum^® Lab Services Manager

Test Code^a

CPT Code(s)^b